ChEMBL ligand: CHEMBL549344 (Cpg-52852, PF-4878691)
TLR7/Toll-like receptor 7 in Human [ChEMBL: CHEMBL5936] [GtoPdb: 1757] [UniProtKB: Q9NYK1] TLR7/Toll-like receptor 7 in Mouse [ChEMBL: CHEMBL6085] [GtoPdb: 1757] [UniProtKB: P58681] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
TLR7/Toll-like receptor 7 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5936] [GtoPdb: 1757] [UniProtKB: Q9NYK1]
ChEMBL	Agonist activity at human TLR7 expressed in HEK293 cells by NFkappaB SEAP reporter gene assay	B	5.58	pEC50	2657	nM	EC50	Bioorg Med Chem Lett (2013) 23: 669-672 [PMID:23265901]
GtoPdb	-	-	5.58	pEC50	2657	nM	EC50	Bioorg Med Chem Lett (2013) 23: 669-72 [PMID:23265901]
TLR7/Toll-like receptor 7 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6085] [GtoPdb: 1757] [UniProtKB: P58681]
ChEMBL	Agonist activity at mouse TLR7	B	5.21	pEC50	6224	nM	EC50	Bioorg Med Chem Lett (2013) 23: 669-672 [PMID:23265901]
GtoPdb	-	-	5.21	pEC50	6224	nM	EC50	Bioorg Med Chem Lett (2013) 23: 669-72 [PMID:23265901]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]