CCL11 [Ligand Id: 769] activity data from GtoPdb

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  • CCR2 in Human [GtoPdb: 59] [UniProtKB: P41597]
Created with Highcharts 10.3.3ValuesChart context menuCCR2pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • CCR3 in Human [GtoPdb: 60] [UniProtKB: P51677]
Created with Highcharts 10.3.3ValuesChart context menuCCR3pKd HumanpKi HumanpIC50 HumanpEC50 Human024681012Highcharts.com
  • CCR5 in Human [GtoPdb: 62] [UniProtKB: P51681]
Created with Highcharts 10.3.3ValuesChart context menuCCR5pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • CXCR3 in Human [GtoPdb: 70] [UniProtKB: P49682]
Created with Highcharts 10.3.3ValuesChart context menuCXCR3pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CCR2 in Human [GtoPdb: 59] [UniProtKB: P41597]
GtoPdb - - 7.7 pIC50 - - - J Biol Chem (2003) 278: 10928-33 [PMID:12554737];
Cytokine (2004) 27: 38-46 [PMID:15207250]
CCR3 in Human [GtoPdb: 60] [UniProtKB: P51677]
GtoPdb - - 10 pKi - - - J Exp Med (1996) 183: 2349-54 [PMID:8642344]
GtoPdb - - 9 pIC50 1 nM IC50 J Clin Invest (1997) 100: 1137-43 [PMID:9276730];
J Biol Chem (1999) 274: 27975-80 [PMID:10488147];
J Pharmacol Exp Ther (2006) 317: 244-50 [PMID:16339911];
Genes Immun (2003) 4: 245-50 [PMID:12761559];
J Biol Chem (2000) 275: 25985-92 [PMID:10854442]
CCR5 in Human [GtoPdb: 62] [UniProtKB: P51681]
GtoPdb - - 7.7 pIC50 - - - Blood (1999) 94: 1899-905 [PMID:10477718]
CXCR3 in Human [GtoPdb: 70] [UniProtKB: P49682]
GtoPdb - - 7.2 pKi - - - J Biol Chem (1998) 273: 18288-91 [PMID:9660793]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.