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ChEMBL ligand: CHEMBL325055 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Angiotensin-converting enzyme in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1808] [GtoPdb: 1613] [UniProtKB: P12821] | ||||||||
GtoPdb | - | - | 8 | pKi | 9.8 | nM | Ki | Med Chem (2005) 1: 71-104 [PMID:16789888] |
ChEMBL | Inhibitory activity against angiotensin I converting enzyme (ACE) | B | 8.01 | pKi | 9.8 | nM | Ki | J. Med. Chem. (2000) 43: 305-341 [PMID:10669559] |
Neutral endopeptidase in Human [GtoPdb: 1611] [UniProtKB: P08473] | ||||||||
GtoPdb | - | - | 8.3 | pKi | 5.6 | nM | Ki | Med Chem (2005) 1: 321-6 [PMID:16789889] |
Neutral endopeptidase/Neprilysin in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3369] [GtoPdb: 1611] [UniProtKB: P07861] | ||||||||
ChEMBL | Inhibitory activity against neutral Endopeptidase | B | 8.25 | pKi | 5.6 | nM | Ki | J. Med. Chem. (2000) 43: 305-341 [PMID:10669559] |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]