MF266-1 [Ligand Id: 6068] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL185346 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| EP1 receptor/Prostanoid EP1 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1811] [GtoPdb: 340] [UniProtKB: P34995] | ||||||||
| ChEMBL | Binding affinity against Prostaglandin E receptor in presence of 2% human serum albumin | B | 8.3 | pKi | 5 | nM | Ki | Bioorg Med Chem Lett (2005) 15: 1155-1160 [PMID:15686932] |
| ChEMBL | Binding affinity against Prostaglandin E receptor was determined in human | B | 8.4 | pKi | 4 | nM | Ki | Bioorg Med Chem Lett (2005) 15: 1155-1160 [PMID:15686932] |
| GtoPdb | - | - | 8.44 | pKi | 3.6 | nM | Ki | J Pharmacol Exp Ther (2008) 325: 425-34 [PMID:18287210] |
| TP receptor/Thromboxane A2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2069] [GtoPdb: 346] [UniProtKB: P21731] | ||||||||
| ChEMBL | Binding affinity against human Prostanoid TP receptor | B | 6.66 | pKi | 220 | nM | Ki | Bioorg Med Chem Lett (2005) 15: 1155-1160 [PMID:15686932] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
