ChEMBL ligand: CHEMBL261491 (Go-6893)
L-type calcium channel alpha 1C/beta 2A in Rabbit [ChEMBL: CHEMBL3638171] [UniProtKB: P15381, P54288] There should be some charts here, you may need to enable JavaScript!
protein kinase C alpha in Human [GtoPdb: 1482] [UniProtKB: P17252] There should be some charts here, you may need to enable JavaScript!
protein kinase C beta in Human [GtoPdb: 1483] [UniProtKB: P05771] There should be some charts here, you may need to enable JavaScript!
protein kinase C gamma in Human [GtoPdb: 1484] [UniProtKB: P05129] There should be some charts here, you may need to enable JavaScript!
protein kinase C delta in Human [GtoPdb: 1485] [UniProtKB: Q05655] There should be some charts here, you may need to enable JavaScript!
protein kinase C zeta in Human [GtoPdb: 1491] [UniProtKB: Q05513] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
L-type calcium channel alpha 1C/beta 2A in Rabbit (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL3638171] [UniProtKB: P15381, P54288]
ChEMBL	Inhibition of Cav1.2 calcium current measured using whole cell patch clamp in human HEK293 cells transfected with rabbit L-type calcium channel subunits	F	4.7	pIC50	20000	nM	IC50	IC50 data for the L-type calcium channel extracted from a set of literature articles
protein kinase C alpha in Human [GtoPdb: 1482] [UniProtKB: P17252]
GtoPdb	-	-	8.15	pIC50	7	nM	IC50	FEBS Lett (1996) 392: 77-80 [PMID:8772178]
protein kinase C beta in Human [GtoPdb: 1483] [UniProtKB: P05771]
GtoPdb	-	-	8.15	pIC50	7	nM	IC50	FEBS Lett (1996) 392: 77-80 [PMID:8772178]
protein kinase C gamma in Human [GtoPdb: 1484] [UniProtKB: P05129]
GtoPdb	-	-	8.22	pIC50	6	nM	IC50	FEBS Lett (1996) 392: 77-80 [PMID:8772178]
protein kinase C delta in Human [GtoPdb: 1485] [UniProtKB: Q05655]
GtoPdb	-	-	8	pIC50	10	nM	IC50	FEBS Lett (1996) 392: 77-80 [PMID:8772178]
protein kinase C zeta in Human [GtoPdb: 1491] [UniProtKB: Q05513]
GtoPdb	-	-	7.22	pIC50	60	nM	IC50	FEBS Lett (1996) 392: 77-80 [PMID:8772178]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]