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ChEMBL ligand: CHEMBL1526258 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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OXE receptor/Oxoeicosanoid receptor 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1628461] [GtoPdb: 271] [UniProtKB: Q8TDS5] | ||||||||
ChEMBL | Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins followed by 5-oxo-ETE addition by fluorescence assay | F | 6.3 | pIC50 | 500 | nM | IC50 | J Med Chem (2018) 61: 5934-5948 [PMID:29972644] |
GPR31 in Mouse [GtoPdb: 98] [UniProtKB: F8VQN3] | ||||||||
GtoPdb | - | - | 9.55 | pEC50 | 0.28 | nM | EC50 | J Biol Chem (2011) 286: 33832-40 [PMID:21712392] |
BLT2 receptor in Human [GtoPdb: 268] [UniProtKB: Q9NPC1] | ||||||||
GtoPdb | - | - | 7.52 | pEC50 | >30 | nM | EC50 | J Biol Chem (2001) 276: 12454-9 [PMID:11278893] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]