[3H]LSD [Ligand Id: 219] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL463207 ([3H]LSD)
  • 5-HT2A receptor/Serotonin 2a (5-HT2a) receptor in Human [ChEMBL: CHEMBL224] [GtoPdb: 6] [UniProtKB: P28223]
  • This target only has 0 pki data point
  • 0
1 CHEMBL463207_lig_chart_1 Serotonin 2a (5-HT2a) receptor Human
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  • 5-HT2C receptor/Serotonin 2c (5-HT2c) receptor in Human [ChEMBL: CHEMBL225] [GtoPdb: 8] [UniProtKB: P28335]
  • This target only has 0 pki data point
  • 0
2 CHEMBL463207_lig_chart_2 Serotonin 2c (5-HT2c) receptor Human
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  • 5-HT2B receptor in Human [GtoPdb: 7] [UniProtKB: P41595]
  • This target only has 0 pki data point
  • 0
3 CHEMBL463207_lig_chart_3 5-HT2B receptor Human
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  • 5-HT6 receptor in Human [GtoPdb: 11] [UniProtKB: P50406]
  • 5-HT6 receptor in Rat [GtoPdb: 11] [UniProtKB: P31388]
  • This target only has 0 pki data point
  • 0
4 CHEMBL463207_lig_chart_4 5-HT6 receptor HumanRat
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  • 5-HT7 receptor in Human [GtoPdb: 12] [UniProtKB: P34969]
  • 5-HT7 receptor in Rat [GtoPdb: 12] [UniProtKB: P32305]
  • This target only has 0 pki data point
  • 0
5 CHEMBL463207_lig_chart_5 5-HT7 receptor HumanRat
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
5-HT2A receptor/Serotonin 2a (5-HT2a) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL224] [GtoPdb: 6] [UniProtKB: P28223]
ChEMBL Binding affinity to human 5HT2A receptor expressed in HEK293 cells by saturation binding method B 7.67 pKd 21.17 nM Kd J. Nat. Prod. (2006) 69: 1421-1424 [PMID:17067154]
5-HT2C receptor/Serotonin 2c (5-HT2c) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL225] [GtoPdb: 8] [UniProtKB: P28335]
ChEMBL Binding affinity to human 5HT2C receptor expressed in HEK293 cells by saturation binding method B 7.28 pKd 52.84 nM Kd J. Nat. Prod. (2006) 69: 1421-1424 [PMID:17067154]
5-HT2B receptor in Human [GtoPdb: 7] [UniProtKB: P41595]
GtoPdb - - 8.7 pKd 2.1 nM Kd Life Sci (2003) 73: 193-207 [PMID:12738034]
5-HT6 receptor in Human [GtoPdb: 11] [UniProtKB: P50406]
GtoPdb - - 8.7 pKd 2 nM Kd Mol Pharmacol (1997) 52: 515-523 [PMID:9284367]
5-HT6 receptor in Rat [GtoPdb: 11] [UniProtKB: P31388]
GtoPdb - - 8.7 pKd - - - Neuropharmacology (1997) 36: 713-20 [PMID:9225298];
Neuropsychopharmacology (1999) 20: 612-27 [PMID:10327430]
5-HT7 receptor in Human [GtoPdb: 12] [UniProtKB: P34969]
GtoPdb - - 8.6 pKd 2.51 nM Kd FEBS Lett (1997) 413: 489-94 [PMID:9303561]
5-HT7 receptor in Rat [GtoPdb: 12] [UniProtKB: P32305]
GtoPdb - - 8.2 pKd - - - Neuropsychopharmacology (1999) 20: 612-27 [PMID:10327430]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]