SA-57 [Ligand Id: 11815] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL457918 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Fatty acid amide hydrolase/Anandamide amidohydrolase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2243] [GtoPdb: 1400] [UniProtKB: O00519] | ||||||||
| ChEMBL | Inhibition of FAAH | B | 7.89 | pIC50 | 13 | nM | IC50 | J Med Chem (2008) 51: 7327-7343 [PMID:18983142] |
| GtoPdb | - | - | 8.72 | pIC50 | 1.9 | nM | IC50 | ACS Chem Neurosci (2012) 3: 418-26 [PMID:22860211] |
| Fatty acid amide hydrolase in Mouse [GtoPdb: 1400] [UniProtKB: O08914] | ||||||||
| GtoPdb | - | - | 8.49 | pIC50 | 3.2 | nM | IC50 | ACS Chem Neurosci (2012) 3: 418-26 [PMID:22860211] |
| monoacylglycerol lipase in Human [GtoPdb: 1399] [UniProtKB: Q99685] | ||||||||
| GtoPdb | - | - | 5.85 | pIC50 | 1400 | nM | IC50 | ACS Chem Neurosci (2012) 3: 418-26 [PMID:22860211] |
| monoacylglycerol lipase in Mouse [GtoPdb: 1399] [UniProtKB: O35678] | ||||||||
| GtoPdb | - | - | 6.39 | pIC50 | 410 | nM | IC50 | ACS Chem Neurosci (2012) 3: 418-26 [PMID:22860211] |
| αβ-Hydrolase 6 in Mouse [GtoPdb: 2919] [UniProtKB: Q8R2Y0] | ||||||||
| GtoPdb | - | - | 6.19 | pIC50 | 650 | nM | IC50 | ACS Chem Neurosci (2012) 3: 418-26 [PMID:22860211] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
