K777 [Ligand Id: 11515] activity data from GtoPdb

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  • cathepsin B in Human [GtoPdb: 2343] [UniProtKB: P07858]
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  • cathepsin K in Human [GtoPdb: 2350] [UniProtKB: P43235]
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  • cathepsin L in Human [GtoPdb: 2351] [UniProtKB: P07711]
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  • cathepsin S in Human [GtoPdb: 2353] [UniProtKB: P25774]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
cathepsin B in Human [GtoPdb: 2343] [UniProtKB: P07858]
GtoPdb - - 5.52 pKi 3000 nM Ki ACS Chem Biol (2021) 16: 642-650 [PMID:33787221]
cathepsin K in Human [GtoPdb: 2350] [UniProtKB: P43235]
GtoPdb - - 6.4 pKi 400 nM Ki ACS Chem Biol (2021) 16: 642-650 [PMID:33787221]
cathepsin L in Human [GtoPdb: 2351] [UniProtKB: P07711]
GtoPdb - - 7.3 pKi 50 nM Ki ACS Chem Biol (2021) 16: 642-650 [PMID:33787221]
cathepsin S in Human [GtoPdb: 2353] [UniProtKB: P25774]
GtoPdb - - 8.7 pKi 2 nM Ki ACS Chem Biol (2021) 16: 642-650 [PMID:33787221]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.