ChEMBL ligand: CHEMBL4210652
glutathione S-transferase omega 1/Glutathione transferase omega 1 in Human [ChEMBL: CHEMBL3174] [GtoPdb: 3110] [UniProtKB: P78417] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
glutathione S-transferase omega 1/Glutathione transferase omega 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3174] [GtoPdb: 3110] [UniProtKB: P78417]
ChEMBL	Inhibition of recombinant GSTO1-1 (unknown origin) expressed in Escherichia coli assessed as inhibitor constant using S-(4-nitrophenacyl)glutathione as substrate preincubated for 1 to 6 mins followed by substrate addition by spectrophotmetric analysis	B	6.36	pKi	440	nM	Ki	J Med Chem (2020) 63: 2894-2914 [PMID:32105470]
ChEMBL	Inhibition of recombinant GSTO1-1 (unknown origin) expressed in Escherichia coli using S-(4-nitrophenacyl)glutathione as substrate preincubated for 2 mins followed by substrate addition by 4-NPG assay	B	6.89	pIC50	130	nM	IC50	J Med Chem (2020) 63: 2894-2914 [PMID:32105470]
GtoPdb	-	-	6.89	pIC50	130	nM	IC50	J Med Chem (2020) 63: 2894-2914 [PMID:32105470]
ChEMBL	Inhibition of GSTO1-1 (unknown origin) by enzymatic assay	B	7.51	pIC50	31	nM	IC50	J Med Chem (2018) 61: 7448-7470 [PMID:29652143]
ChEMBL	Inhibition of CMFDA binding to human N-terminal 6x-His-tagged GSTO1-1 preincubated for 30 mins followed by CMFDA addition and measured after 30 mins by in-gel fluorescence binding assay	B	7.68	pIC50	21	nM	IC50	J Med Chem (2019) 62: 3068-3087 [PMID:30735370]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]