BMS-986260 [Ligand Id: 10662] activity data from GtoPdb

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  • activin A receptor type 1 in Human [GtoPdb: 1785] [UniProtKB: Q04771]
Created with Highcharts 10.3.3ValuesChart context menuactivin A receptor type 1pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • activin A receptor type 1B in Human [GtoPdb: 1787] [UniProtKB: P36896]
Created with Highcharts 10.3.3ValuesChart context menuactivin A receptor type 1BpKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • transforming growth factor beta receptor 1 in Human [GtoPdb: 1788] [UniProtKB: P36897]
Created with Highcharts 10.3.3ValuesChart context menutransforming growth factor beta receptor 1pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
activin A receptor type 1 in Human [GtoPdb: 1785] [UniProtKB: Q04771]
GtoPdb - - 7.15 pIC50 70.4 nM IC50 ACS Med Chem Lett (2020) 11: 172-178 [PMID:32071685]
activin A receptor type 1B in Human [GtoPdb: 1787] [UniProtKB: P36896]
GtoPdb - - 7.48 pIC50 33.3 nM IC50 ACS Med Chem Lett (2020) 11: 172-178 [PMID:32071685]
transforming growth factor beta receptor 1 in Human [GtoPdb: 1788] [UniProtKB: P36897]
GtoPdb - - 8.8 pIC50 1.6 nM IC50 ACS Med Chem Lett (2020) 11: 172-178 [PMID:32071685]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.