AZD3965 [Ligand Id: 10605] activity data from GtoPdb

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  • Monocarboxylate transporter 1 in Human [GtoPdb: 988] [UniProtKB: P53985]
  • This target only has 1 pki data point
  • 8.49
1 _lig_chart_1 Monocarboxylate transporter 1 Human
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  • Monocarboxylate transporter 2 in Human [GtoPdb: 990] [UniProtKB: O60669]
  • This target only has 1 pki data point
  • 7.7
2 _lig_chart_2 Monocarboxylate transporter 2 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Monocarboxylate transporter 1 in Human [GtoPdb: 988] [UniProtKB: P53985]
GtoPdb AZD3965 binding affinity to yeast membranes expressing recombinant human MCT1 by displacement of [3H]-MCT1 ligand. - 8.49 pKi 3.2 nM Ki Oncotarget (2017) 8: 69219-69236 [PMID:29050199]
Monocarboxylate transporter 2 in Human [GtoPdb: 990] [UniProtKB: O60669]
GtoPdb AZD3965 binding affinity to yeast membranes expressing recombinant human MCT2 by displacement of [3H]-MCT2 ligand. - 7.7 pKi 20 nM Ki Oncotarget (2017) 8: 69219-69236 [PMID:29050199]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.