carotegrast [Ligand Id: 10511] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • integrin α4β1 in Human [GtoPdb: 2580]
Created with Highcharts 10.3.3ValuesChart context menuintegrin α4β1pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • integrin α4β7 in Human [GtoPdb: 2770]
Created with Highcharts 10.3.3ValuesChart context menuintegrin α4β7pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
integrin α4β1 in Human [GtoPdb: 2580]
GtoPdb Measuring inhibition of binding between &alpha4;β1 integrin expressed by Jurkat cells and immobilised VCAM-1, in the presence of test compound. - 7.24 pIC50 57 nM IC50 US20110065918A1. New phenylalanine derivatives (2011)
integrin α4β7 in Human [GtoPdb: 2770]
GtoPdb Measuring inhibition of binding between &alpha4;β7 integrin expressed by RPMI-8866 cells and immobilised VCAM-1, in the presence of test compound. - 8.48 pIC50 3.3 nM IC50 US20110065918A1. New phenylalanine derivatives (2011)

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.