compound 25 [PMID: 31260299] [Ligand Id: 10428] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • BLK proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 1940] [UniProtKB: P51451]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 BLK proto-oncogene, Src family tyrosine kinase Human
There should be some charts here, you may need to enable JavaScript!
  • Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 Bruton tyrosine kinase Human
There should be some charts here, you may need to enable JavaScript!
  • FYN proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2026] [UniProtKB: P06241]
  • This target only has 0 pki data point
  • 0
3 _lig_chart_3 FYN proto-oncogene, Src family tyrosine kinase Human
There should be some charts here, you may need to enable JavaScript!
  • IL2 inducible T cell kinase in Human [GtoPdb: 2046] [UniProtKB: Q08881]
  • This target only has 0 pki data point
  • 0
4 _lig_chart_4 IL2 inducible T cell kinase Human
There should be some charts here, you may need to enable JavaScript!
  • SRC proto-oncogene, non-receptor tyrosine kinase in Human [GtoPdb: 2206] [UniProtKB: P12931]
  • This target only has 0 pki data point
  • 0
5 _lig_chart_5 SRC proto-oncogene, non-receptor tyrosine kinase Human
There should be some charts here, you may need to enable JavaScript!
  • tec protein tyrosine kinase in Human [GtoPdb: 2238] [UniProtKB: P42680]
  • This target only has 0 pki data point
  • 0
6 _lig_chart_6 tec protein tyrosine kinase Human
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
BLK proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 1940] [UniProtKB: P51451]
GtoPdb - - 6.82 pIC50 150 nM IC50 J Med Chem (2019) 62: 6561-6574 [PMID:31260299]
Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
GtoPdb - - 8.28 pIC50 5.3 nM IC50 J Med Chem (2019) 62: 6561-6574 [PMID:31260299]
FYN proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2026] [UniProtKB: P06241]
GtoPdb - - 6.78 pIC50 165.2 nM IC50 J Med Chem (2019) 62: 6561-6574 [PMID:31260299]
IL2 inducible T cell kinase in Human [GtoPdb: 2046] [UniProtKB: Q08881]
GtoPdb - - 6.51 pIC50 306.9 nM IC50 J Med Chem (2019) 62: 6561-6574 [PMID:31260299]
SRC proto-oncogene, non-receptor tyrosine kinase in Human [GtoPdb: 2206] [UniProtKB: P12931]
GtoPdb - - 6.04 pIC50 902.5 nM IC50 J Med Chem (2019) 62: 6561-6574 [PMID:31260299]
tec protein tyrosine kinase in Human [GtoPdb: 2238] [UniProtKB: P42680]
GtoPdb - - 6.64 pIC50 227 nM IC50 J Med Chem (2019) 62: 6561-6574 [PMID:31260299]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.