solriamfetol [Ligand Id: 10342] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| NET in Human [GtoPdb: 926] [UniProtKB: P23975] | ||||||||
| GtoPdb | In a radioligand binding assay using HEK293 cells expressing hNET. | - | 5.43 | pKi | 3700 | nM | Ki | J Pharmacol Exp Ther (2018) 366: 367-376 [PMID:29891587] |
| GtoPdb | In a NE reuptake assay in HEK293 cells expressing hNET. | - | 5.36 | pIC50 | 4400 | nM | IC50 | J Pharmacol Exp Ther (2018) 366: 367-376 [PMID:29891587] |
| DAT in Human [GtoPdb: 927] [UniProtKB: Q01959] | ||||||||
| GtoPdb | In a radioligand binding assay using HEK293 cells expressing hDAT. | - | 4.85 | pKi | 14200 | nM | Ki | J Pharmacol Exp Ther (2018) 366: 367-376 [PMID:29891587] |
| GtoPdb | In a DA reuptake assay in HEK293 cells expressing hDAT. | - | 5.54 | pIC50 | 2900 | nM | IC50 | J Pharmacol Exp Ther (2018) 366: 367-376 [PMID:29891587] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
