NF-κB regulators

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Targets

Targets of relevance to immunopharmacology are highlighted in blue

IκBζ (NFKB inhibitor zeta) Show summary »« Hide summary More detailed page go icon to follow link

Target Id	3008
Nomenclature	NFKB inhibitor zeta
Common abbreviation	IκBζ
Previous and unofficial names	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta \| nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor \| IL-1 inducible nuclear ankyrin-repeat protein \| molecule possessing ankyrin repeats induced by lipopolysaccharide \| NF-kappa-B inhibitor zeta \| nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta \| MAIL \| INAP
Genes	NFKBIZ (Hs), Nfkbiz (Mm), Nfkbiz (Rn)
Ensembl ID	ENSG00000144802 (Hs), ENSMUSG00000035356 (Mm), ENSRNOG00000031163 (Rn)
UniProtKB AC	Q9BYH8 (Hs), Q9EST8 (Mm)
Comment	IκBζ is an atypical member of the IκB protein family, that like Bcl3 and IκBNS resides in the nucleus. IκBζ is involved in regulation of NF-κB transcription factor complexes, principally as an inhibitor of NF-κB transcriptional activity.

How to cite this family page

Database page citation:

NF-κB regulators. Accessed on 25/03/2023. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=996.

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets. Br J Pharmacol. 178 Suppl 1:S1-S26.