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Immune checkpoint modulators C

Overview

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This family contains agents that are able to modulate the regulatory mechanisms that control the immune responses of antigen-specific T cells, including those that are approved immunotherapeutics.

Ligands

Ligands of relevance to immunopharmacology are highlighted in blue

abatacept Show summary » More detailed page

belatacept Show summary » More detailed page

lulizumab pegol Show summary » More detailed page

relatlimab Show summary » More detailed page

ipilimumab Show summary » More detailed page

pembrolizumab Show summary » More detailed page

tremelimumab Show summary » More detailed page

BGB-A317 Show summary » More detailed page

nivolumab Show summary » More detailed page

moxetumomab pasudotox Show summary » More detailed page

lintuzumab Show summary » More detailed page

vadastuximab talirine Show summary » More detailed page

gemtuzumab ozogamicin Show summary » More detailed page

PD-L1 (programmed cell death 1 ligand 1) {Sp: Human} Show summary » More detailed page

inotuzumab ozogamicin Show summary » More detailed page

cemiplimab Show summary » More detailed page

How to cite this family page

Database page citation:

Immune checkpoint modulators. Accessed on 19/08/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=969.