RSTK functional heteromers | Catalytic receptors | IUPHAR/BPS Guide to IMMUNOPHARMACOLOGY

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Catalytic receptors
Receptor kinases
TKL: Tyrosine kinase-like
Receptor serine/threonine kinase (RSTK) family
RSTK functional heteromers

RSTK functional heteromers C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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For the receptors listed on this page, the exact combination of subunits forming the functional heteromeric receptors is unknown.

Receptors

2588

Targets of relevance to immunopharmacology are highlighted in blue

Complexes

Transforming growth factor β receptor C Show summary »« Hide summary

Bone morphogenetic protein receptors C Show summary »« Hide summary

Growth/differentiation factor receptors C Show summary »« Hide summary

Activin receptors C Show summary »« Hide summary

Target Id

2588

Nomenclature

Activin receptors

Subunits

activin A receptor type 1B (Type I)
activin A receptor type 1C (Type I)
activin A receptor type 2A (Type II)
activin A receptor type 2B (Type II)

Coupling

Smad2, Smad3 [2]

Endogenous agonists

activin A (INHBA, P08476)

activin AB (INHBB, INHBA, P08476, P09529)

activin B (INHBB, P09529)

inhibin A (INHA, INHBA, P05111, P08476)

Comment

Activin receptors are heteromeric complexes comprising activin receptor type I and type II subunits.

Anti-Müllerian hormone receptors C Show summary »« Hide summary

References

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How to cite this family page

Database page citation:

RSTK functional heteromers. Accessed on 20/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=797.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors. Br J Pharmacol. 180 Suppl 2:S241-288.