M79: Prenyl protease 2

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

Targets of relevance to immunopharmacology are highlighted in blue

Ras converting CAAX endopeptidase 1 Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2412

Nomenclature

Ras converting CAAX endopeptidase 1

Previous and unofficial names

Genes

RCE1 (Hs), Rce1 (Mm), Rce1 (Rn)

Ensembl ID

ENSG00000173653 (Hs), ENSMUSG00000024889 (Mm), ENSRNOG00000019468 (Rn)

UniProtKB AC

Q9Y256 (Hs), P57791 (Mm), B0BMW8 (Rn)

EC number

3.4.22.-

Selective inhibitors

CID16197121 pIC₅₀ 6.7 (Activity reported as AU50) [1]

References

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How to cite this family page

Database page citation:

M79: Prenyl protease 2. Accessed on 15/06/2025. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=736.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.