Iota subfamily | Enzymes | IUPHAR/BPS Guide to IMMUNOPHARMACOLOGY

Iota subfamily C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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PKCι, PKCζ are atypical serine/threonine protein kinase C isoforms. In contrast to other PKC enzymes these are not activated by phorbolesters or diacylglycerol.

Enzymes

Targets of relevance to immunopharmacology are highlighted in blue

PKCι (protein kinase C iota) C Show summary »« Hide summary More detailed page go icon to follow link

Target Id

1490

Nomenclature

protein kinase C iota

Common abbreviation

PKCι

Previous and unofficial names

atypical protein kinase C-lambda/iota | Pkcl | protein kinase C

Genes

PRKCI (Hs), Prkci (Mm), Prkci (Rn)

Ensembl ID

ENSG00000163558 (Hs), ENSMUSG00000037643 (Mm), ENSRNOG00000009652 (Rn)

UniProtKB AC

P41743 (Hs), Q62074 (Mm), F1M7Y5 (Rn)

EC number

2.7.11.13

Comment

Known as PKCλ in rodents

PKCζ (protein kinase C zeta) C Show summary »« Hide summary More detailed page go icon to follow link

References

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How to cite this family page

Database page citation:

Iota subfamily. Accessed on 11/10/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=535.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.