LZK subfamily

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Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

Targets of relevance to immunopharmacology are highlighted in blue

DLK (mitogen-activated protein kinase kinase kinase 12) Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2072

Nomenclature

mitogen-activated protein kinase kinase kinase 12

Common abbreviation

DLK

Previous and unofficial names

dual leucine zipper kinase DLK | MAPK-upstream kinase | MEKK12 | MUK | ZPKP1

Genes

MAP3K12 (Hs), Map3k12 (Mm), Map3k12 (Rn)

Ensembl ID

ENSG00000139625 (Hs), ENSMUSG00000023050 (Mm), ENSRNOG00000015134 (Rn)

UniProtKB AC

Q12852 (Hs), Q60700 (Mm), Q63796 (Rn)

EC number

2.7.11.25

LZK (mitogen-activated protein kinase kinase kinase 13) Show summary »« Hide summary More detailed page go icon to follow link

How to cite this family page

Database page citation:

LZK subfamily. Accessed on 01/07/2025. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=523.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.