IL-17 receptor family | Catalytic receptors | IUPHAR/BPS Guide to IMMUNOPHARMACOLOGY

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IL-17 receptor family C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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The IL17 cytokine family consists of six ligands (IL-17A-F), which signal through five receptors (IL-17RA-E).

Receptors

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Targets of relevance to immunopharmacology are highlighted in blue

Complexes

Interleukin-17 receptor C Show summary »« Hide summary More detailed page go icon to follow link

Interleukin-25 receptor C Show summary »« Hide summary More detailed page go icon to follow link

Interleukin-17C receptor C Show summary »« Hide summary More detailed page go icon to follow link

Receptors and Subunits

Interleukin 17 receptor A C Show summary »« Hide summary More detailed page go icon to follow link

Interleukin 17 receptor B C Show summary »« Hide summary More detailed page go icon to follow link

interleukin 17 receptor C C Show summary »« Hide summary More detailed page go icon to follow link

Interleukin-17 receptor D C Show summary »« Hide summary More detailed page go icon to follow link

Interleukin 17 receptor E C Show summary »« Hide summary More detailed page go icon to follow link

Further reading

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* Key recommended reading is highlighted with an asterisk

* Beringer A, Noack M, Miossec P. (2016) IL-17 in Chronic Inflammation: From Discovery to Targeting. Trends Mol Med, 22 (3): 230-241. [PMID:26837266]

* Lubberts E. (2015) The IL-23-IL-17 axis in inflammatory arthritis. Nat Rev Rheumatol, 11 (7): 415-29. [PMID:25907700]

* McGeachy MJ, Cua DJ, Gaffen SL. (2019) The IL-17 Family of Cytokines in Health and Disease. Immunity, 50 (4): 892-906. DOI: 10.1016/j.immuni.2019.03.021 [PMID:30995505]

References

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How to cite this family page

Database page citation:

IL-17 receptor family. Accessed on 13/05/2025. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=313.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors. Br J Pharmacol. 180 Suppl 2:S241-288.