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Interferon receptor family C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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The interferon receptor family includes receptors for type I (α, β κ and ω) and type II (γ) interferons. There are at least 13 different genes encoding IFN-α subunits in a cluster on human chromosome 9p22: α1 (IFNA1, P01562), α2 (IFNA2, P01563), α4 (IFNA4, P05014), α5 (IFNA5, P01569), α6 (IFNA6, P05013), α7 (IFNA7, P01567), α8 (IFNA8, P32881), α10 (IFNA10, P01566), α13 (IFNA13, P01562), α14 (IFNA14, P01570), α16 (IFNA16, P05015), α17 (IFNA17, P01571) and α21 (IFNA21, P01568).

Receptors

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Targets of relevance to immunopharmacology are highlighted in blue

Complexes

Interferon-α/β receptor C Show summary » More detailed page go icon to follow link

Interferon-γ receptor C Show summary » More detailed page go icon to follow link

Receptors and Subunits

interferon α/β receptor 1 C Show summary » More detailed page go icon to follow link

Interferon α/β receptor 2 C Show summary » More detailed page go icon to follow link

Interferon γ receptor 1 C Show summary » More detailed page go icon to follow link

Interferon γ receptor 2 C Show summary » More detailed page go icon to follow link

Further reading

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References

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How to cite this family page

Database page citation:

Interferon receptor family. Accessed on 20/04/2021. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=310.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Catalytic receptors. Br J Pharmacol. 176 Suppl 1: S247-S296.