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CYP5, CYP7 and CYP8 families C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Members of this enzyme family catalyse reactions in the pathways that synthesise or catabolise important lipid mediators, steroids and cholesterol.

Enzymes

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Targets of relevance to immunopharmacology are highlighted in blue

Thromboxane-A synthase (CYP5A1) C Show summary » More detailed page go icon to follow link

Cholesterol 7 alpha-hydroxylase (CYP7A1) C Show summary »

CYP7B1 C Show summary »

Prostacyclin synthase (CYP8A1) C Show summary »

CYP8B1 C Show summary »

References

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How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Enzymes. Br J Pharmacol. 176 Issue S1: S297-S396.