P5 P-type ATPases: Mn<sup>2+</sup>-ATPases | Transporters | IUPHAR/BPS Guide to IMMUNOPHARMACOLOGY

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P5 P-type ATPases: Mn²⁺-ATPases

P5 P-type ATPases: Mn²⁺-ATPases C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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P5 subfamily P-type ATPases are cation and lipid pumps that transport inorganic cations and other substrates across cell membranes.

Transporters

Targets of relevance to immunopharmacology are highlighted in blue

ATPase 13A1 C Show summary »« Hide summary

ATPase cation transporting 13A2 C Show summary »« Hide summary

Target Id	3156
Nomenclature	ATPase cation transporting 13A2
Previous and unofficial names	ATPase type 13A2 \| CLN12 \| PARK9 \| Parkinson disease (autosomal recessive) 9 (Kufor-Rakeb syndrome)
Genes	ATP13A2 (Hs), Atp13a2 (Mm), Atp13a2 (Rn)
Ensembl ID	ENSG00000159363 (Hs), ENSMUSG00000036622 (Mm), ENSRNOG00000008052 (Rn)
UniProtKB AC	Q9NQ11 (Hs)

ATPase 13A3 C Show summary »« Hide summary

Target Id	3157
Nomenclature	ATPase 13A3
Previous and unofficial names	AFURS1 \| ATPase family homolog up regulated in senescence cells
Genes	ATP13A3 (Hs), Atp13a3 (Mm), Atp13a3 (Rn)
Ensembl ID	ENSG00000133657 (Hs), ENSMUSG00000022533 (Mm), ENSRNOG00000066681 (Rn)
UniProtKB AC	Q9H7F0 (Hs), Q5XF89 (Mm)
Comment	Identified as an important component of the mammalian polyamine transport system [1].

ATPase 13A4 C Show summary »« Hide summary

ATPase 13A5 C Show summary »« Hide summary

References

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How to cite this family page

Database page citation:

P5 P-type ATPases: Mn²⁺-ATPases. Accessed on 19/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1046.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.