SLC62 Pyrophosphate transporters | Transporters | IUPHAR/BPS Guide to IMMUNOPHARMACOLOGY

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SLC superfamily of solute carriers
SLC62 Pyrophosphate transporters

SLC62 Pyrophosphate transporters C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Transporters

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ANKH inorganic pyrophosphate transport regulator / SLC62A1 C Show summary »« Hide summary

Target Id

3046

Nomenclature

ANKH inorganic pyrophosphate transport regulator

Systematic nomenclature

SLC62A1

Genes

ANKH (Hs), Ank (Mm), Ankh (Rn)

Ensembl ID

ENSG00000154122 (Hs), ENSMUSG00000022265 (Mm), ENSRNOG00000010960 (Rn)

UniProtKB AC

Q9HCJ1 (Hs), Q9JHZ2 (Mm), P58366 (Rn)

RESOLUTE

ANKH (Hs)

Substrates

Pyrophosphate [2]

Comment

ANKH/SLC62 is a putative 8TM membrane protein, also known as progressive ankylosis protein homolog. Mutations in this protein are associated with bone and joint abnormalities. It is expressed in kidney and bone [1].

References

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How to cite this family page

Database page citation:

SLC62 Pyrophosphate transporters. Accessed on 23/03/2023. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1014.

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters. Br J Pharmacol. 178 Suppl 1:S412-S513.

SLC62 Pyrophosphate transporters C

Transporters

Targets of relevance to immunopharmacology are highlighted in blue

Further reading

References

How to cite this family page