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Human immunodeficiency virus type 1, susceptibility to

Disease ID:441
Name:Human immunodeficiency virus type 1, susceptibility to
Associated with:8 targets
Synonyms
Human immunodeficiency virus infectious disease
Database Links
Disease Ontology: DOID:526
OMIM: 609423
Orphanet: ORPHA319269

Targets

CCR2
CCR5
CX3CR1
chemerin receptor 1
References:  1
Interleukin-4 receptor subunit α
Role:  A polymorphism in IL4R (I50V) is associated with slower progression to AIDs in HIV-positive individuals.
References:  2
TLR3
TLR7
TLR9

Ligands

No ligand related data available for Human immunodeficiency virus type 1, susceptibility to

References

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1. Mårtensson UE, Fenyö EM, Olde B, Owman C. (2006) Characterization of the human chemerin receptor--ChemR23/CMKLR1--as co-receptor for human and simian immunodeficiency virus infection, and identification of virus-binding receptor domains. Virology, 355 (1): 6-17. [PMID:16904155]

2. Soriano A, Lozano F, Oliva H, García F, Nomdedéu M, De Lazzari E, Rodríguez C, Barrasa A, Lorenzo JI, Del Romero J et al.. (2005) Polymorphisms in the interleukin-4 receptor alpha chain gene influence susceptibility to HIV-1 infection and its progression to AIDS. Immunogenetics, 57 (9): 644-54. [PMID:16189667]