Gene and Protein Information
Species	TM	P Loops	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	6	1	491	2p24.2	KCNS3	potassium voltage-gated channel modifier subfamily S member 3
Mouse	6	1	491	12 5.58 cM	Kcns3	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
Rat	6	1	491	6q15	Kcns3	potassium voltage-gated channel, modifier subfamily S, member 3

Previous and Unofficial Names

delayed-rectifier K(+) channel alpha subunit 3 | voltage-gated potassium channel subunit Kv9.3 | potassium voltage-gated channel, modifier subfamily S, member 3 | potassium voltage-gated channel

Database Links
Alphafold	Q9BQ31 (Hs), Q8BQZ8 (Mm), O88759 (Rn)
Ensembl Gene	ENSG00000170745 (Hs), ENSMUSG00000043673 (Mm), ENSRNOG00000004899 (Rn)
Entrez Gene	3790 (Hs), 238076 (Mm), 83588 (Rn)
Human Protein Atlas	ENSG00000170745 (Hs)
KEGG Gene	hsa:3790 (Hs), mmu:238076 (Mm), rno:83588 (Rn)
OMIM	603888 (Hs)
Pharos	Q9BQ31 (Hs)
RefSeq Nucleotide	NM_002252 (Hs), NM_173417 (Mm), NM_031778 (Rn)
RefSeq Protein	NP_002243 (Hs), NP_775593 (Mm), NP_113966 (Rn)
UniProtKB	Q9BQ31 (Hs), Q8BQZ8 (Mm), O88759 (Rn)
Wikipedia	KCNS3 (Hs)

Ion Selectivity and Conductance
Species:  None Macroscopic current rectification:  Modifiers/ Silencer References:

Activator Comments

Kv9.3 / Kv2.1 form ATP-dependent delayed rectifier channels in oxygen-sensitive pulmonary myocytes. Hypoxia blocks Kv9.3 / Kv2.1 channels [1-5]

Gating Inhibitor Comments

Kv9.3 / Kv2.1 heteromers inactivate in a fast and complete fashion from intermediate closed states but in a slow and incomplete manner from open states [2] Kv2.1 / Kv9.3 heteromeric channels are inhibited by hypoxia in the voltage range of the PA VSMC EM [1]

Tissue Distribution
Heart, brain, spleen, lung, kidney, artery Species:  Rat Technique:  Northern Blot References:  3,5

General Comments
The human Kv9.3 gene is intronless across the coding region 3'-UTR and all of the analysed 5'-UTR [4]