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Gene and Protein Information | ||||||
Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | - | 173 | 16q23.2 | GCSH | glycine cleavage system protein H | 1-2 |
Mouse | - | 170 | 8 E1 | Gcsh | glycine cleavage system protein H (aminomethyl carrier) | |
Rat | - | 170 | 19q12 | Gcsh | glycine cleavage system protein H |
Database Links | |
Alphafold | P23434 (Hs), Q91WK5 (Mm), Q5I0P2 (Rn) |
Ensembl Gene | ENSG00000140905 (Hs), ENSMUSG00000034424 (Mm), ENSRNOG00000011535 (Rn) |
Entrez Gene | 2653 (Hs), 68133 (Mm), 171133 (Rn) |
Human Protein Atlas | ENSG00000140905 (Hs) |
KEGG Gene | hsa:2653 (Hs), mmu:68133 (Mm), rno:171133 (Rn) |
OMIM | 238330 (Hs) |
Pharos | P23434 (Hs) |
RefSeq Nucleotide | NM_004483 (Hs), NM_026572 (Mm), NM_133598 (Rn) |
RefSeq Protein | NP_004474 (Hs), NP_080848 (Mm), NP_598282 (Rn) |
UniProtKB | P23434 (Hs), Q91WK5 (Mm), Q5I0P2 (Rn) |
Wikipedia | GCSH (Hs) |
General Comments |
GCSH is a component of the glycine cleavage system. |
1. Fujiwara K, Okamura-Ikeda K, Hayasaka K, Motokawa Y. (1991) The primary structure of human H-protein of the glycine cleavage system deduced by cDNA cloning. Biochem Biophys Res Commun, 176 (2): 711-6. [PMID:2025283]
2. Koyata H, Hiraga K. (1991) The glycine cleavage system: structure of a cDNA encoding human H-protein, and partial characterization of its gene in patients with hyperglycinemias. Am J Hum Genet, 48 (2): 351-61. [PMID:1671321]
Glycine recycling: glycine cleavage system protein H. Last modified on 25/09/2019. Accessed on 09/12/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=3098.