Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	727	2p21	PREPL	prolyl endopeptidase like
Mouse	-	725	17 E4	Prepl	prolyl endopeptidase-like
Rat	-	726	6q12	Prepl	prolyl endopeptidase-like

Previous and Unofficial Names

prolyl endopeptidase-like

Database Links
Specialist databases
MEROPS	S09.015 (Hs)
Other databases
Alphafold	Q4J6C6 (Hs), Q8C167 (Mm), Q5HZA6 (Rn)
BRENDA	3.4.21.26
CATH/Gene3D	3.40.50.1820
ChEMBL Target	CHEMBL2189128 (Hs)
Ensembl Gene	ENSG00000138078 (Hs), ENSMUSG00000024127 (Mm), ENSRNOG00000007326 (Rn)
Entrez Gene	9581 (Hs), 213760 (Mm), 298771 (Rn)
Human Protein Atlas	ENSG00000138078 (Hs)
KEGG Enzyme	3.4.21.26
KEGG Gene	hsa:9581 (Hs), mmu:213760 (Mm), rno:298771 (Rn)
OMIM	609557 (Hs)
Pharos	Q4J6C6 (Hs)
RefSeq Nucleotide	NM_001171603 (Hs), NM_001163622 (Mm), NM_001010951 (Rn)
RefSeq Protein	NP_001165074 (Hs), NP_001157094 (Mm), NP_001010951 (Rn)
UniProtKB	Q4J6C6 (Hs), Q8C167 (Mm), Q5HZA6 (Rn)
Wikipedia	PREPL (Hs)

Enzyme Reaction
EC Number: 3.4.21.26

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Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference compound 8 [PMID: 21692504] Mm Inhibition 5.2 pIC50 1 ⤷ pIC50 5.2 (IC50 6x10-6 M) [1] Description: In a substrate free assay.