Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	909	10q26.2	ADAM12	ADAM metallopeptidase domain 12
Mouse	1	903	7 F3	Adam12	ADAM metallopeptidase domain 12
Rat	-	-	1q41	Adam12	ADAM metallopeptidase domain 12

Previous and Unofficial Names

MCMPMltna | MLTN

Database Links
Specialist databases
MEROPS	M12.212 (Hs)
Other databases
Alphafold	O43184 (Hs), Q61824 (Mm)
BRENDA	3.4.24.-
CATH/Gene3D	3.40.390.10, 4.10.70.10
ChEMBL Target	CHEMBL5030 (Hs)
Ensembl Gene	ENSG00000148848 (Hs), ENSMUSG00000054555 (Mm), ENSRNOG00000018384 (Rn)
Entrez Gene	8038 (Hs), 11489 (Mm), 679837 (Rn)
Human Protein Atlas	ENSG00000148848 (Hs)
KEGG Enzyme	3.4.24.-
KEGG Gene	hsa:8038 (Hs), mmu:11489 (Mm), rno:679837 (Rn)
OMIM	602714 (Hs)
Pharos	O43184 (Hs)
RefSeq Nucleotide	NM_003474 (Hs), NM_021641 (Hs), NM_007400 (Mm)
RefSeq Protein	NP_003465 (Hs), NP_067673 (Hs), NP_031426 (Mm)
UniProtKB	O43184 (Hs), Q61824 (Mm)
Wikipedia	ADAM12 (Hs)

Enzyme Reaction
EC Number: 3.4.24.-

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference ilomastat Hs Inhibition 8.2 pIC50 1 ⤷ pIC50 8.2 (IC50 5.93x10-9 M) [1] Description: Measured in a cell-based assay.