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Arginyl aminopeptidase

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Target not currently curated in GtoImmuPdb

Target id: 1564

Nomenclature: Arginyl aminopeptidase

Family: M1: Aminopeptidase N

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 650 1q32.1 RNPEP arginyl aminopeptidase
Mouse - 650 1 E4 Rnpep arginyl aminopeptidase (aminopeptidase B)
Rat - 650 13q13 Rnpep arginyl aminopeptidase
Previous and Unofficial Names Click here for help
AP-B | arginine aminopeptidase | cytosol aminopeptidase IV | arginyl aminopeptidase (aminopeptidase B)
Database Links Click here for help
Specialist databases
MEROPS M01.014 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction Click here for help
EC Number:

Download all structure-activity data for this target as a CSV file go icon to follow link

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
Lys-thiol Small molecule or natural product Primary target of this compound N/A Inhibition 9.1 pKi 1
pKi 9.1 (Ki 9x10-10 M) [1]


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1. Ocain TD, Rich DH. (1987) L-lysinethiol: a subnanomolar inhibitor of aminopeptidase B. Biochem Biophys Res Commun, 145 (3): 1038-42. [PMID:3111463]

How to cite this page

M1: Aminopeptidase N: Arginyl aminopeptidase. Last modified on 28/07/2015. Accessed on 28/11/2022. IUPHAR/BPS Guide to PHARMACOLOGY,