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The IUPHAR Guide to IMMUNOPHARMACOLOGY ligand list

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GtoImmuPdb ligands only: Ligands which are included in the World Health Organization (WHO) Model List of Essential Medicines (23rd list, 2023).
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Ligand name ID Synonyms
A Back to top
adalimumab Approved drug Immunopharmacology Ligand 4860 D2E7, Humira®
aspirin Approved drug PDB Ligand Immunopharmacology Ligand 4139 Acetophen®, acetylsalicylic acid, Aspirin®
atracurium Approved drug Immunopharmacology Ligand 9537 atracurium besilate, atracurium dibesylate, BW 33A, Tracrium®
azathioprine Approved drug Immunopharmacology Ligand 7120 Azasan®, BW-57-322, Imuran®, Jayempi®
azithromycin Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6510
 
B Back to top
beclometasone Approved drug PDB Ligand Immunopharmacology Ligand 7059 beclomethasone, SCH-18020W
betamethasone Approved drug Immunopharmacology Ligand 7061 SCH-4831
bortezomib Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6391 peptide boronate, PS-341, Velcade®
budesonide Approved drug Immunopharmacology Ligand 7434 Entocort®, Eohilia® (budesonide oral suspension), Jorveza®, Pulmicort®, S-1320, Uceris®
 
C Back to top
chloroquine Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 5535 Aralen®, chloraquine, Malaquin®
clofazimine Approved drug Immunopharmacology Ligand 9184 Lamprene®
cortisol Approved drug PDB Ligand Immunopharmacology Ligand 2868 Acticort®, Efmody®, Plenadren®
cyclosporin A Approved drug Immunopharmacology Ligand 1024 ciclosporin, cyclosporine, cyclosporine A, Ikervis® (opthalmic solution), Neoral®, Sandimmun®, Verkazia® (opthalmic solution)
 
D Back to top
dasatinib Approved drug PDB Ligand Immunopharmacology Ligand 5678 BMS 345825, BMS 354825, BMS 35482513, Sprycel®
dexamethasone Approved drug PDB Ligand Immunopharmacology Ligand 2768 Decadron®, desametasone, fluormethylprednisolone
dopamine Approved drug PDB Ligand Immunopharmacology Ligand 940 3-hydroxytyramine
doxycycline Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6464 BMY-28689, Monodox®, Vibramycin®
 
E Back to top
everolimus Approved drug Immunopharmacology Ligand 5889 Afinitor®, Certican®, RAD-001, RAD001, rapamycin, 42-O-(2-hydroxyethyl)-, Zortress®
 
F Back to top
filgrastim Approved drug Immunopharmacology Ligand 6968 Filcad®, Imumax ®, R-METHUG-CSF
formoterol Approved drug Immunopharmacology Ligand 3465 BD-40A, CGP-25827A, Foradil®, Oxeze/Oxis®, YM-08316
 
H Back to top
hydroxychloroquine Approved drug Immunopharmacology Ligand Antimalarial Ligand 7198 Dolquine®, Plaquenil®
 
I Back to top
ibrutinib Approved drug PDB Ligand Immunopharmacology Ligand 6912 Imbruvica®, PCI-32765
ibuprofen Approved drug Immunopharmacology Ligand 2713 Advil®, Brufen®, ibuprofen lysine, ibuprofen sodium, Motrin®, Nurofen®, U-18573
imatinib Approved drug PDB Ligand Immunopharmacology Ligand 5687 CGP 57148, Gleevec®, Glivec®, STI571
ipratropium Approved drug Immunopharmacology Ligand 325 Atrovent®, Ipraxa®
 
L Back to top
lenalidomide Approved drug Immunopharmacology Ligand 7331 CC-5013, CDC-501, Revlimid®
loratadine Approved drug Immunopharmacology Ligand 7216 Claritin®, SCH-29851
 
M Back to top
metformin Approved drug PDB Ligand Immunopharmacology Ligand 4779 Glucophage®, LA-6023
methimazole Approved drug PDB Ligand Immunopharmacology Ligand 6649 Tapazole®, Thiamazole®
methotrexate Approved drug PDB Ligand Immunopharmacology Ligand 4815 Abitrexate®, amethopterin, Nordimet®, Rasuvo®
methylprednisolone Approved drug Immunopharmacology Ligand 7088 Medrol®, U-67590A
mifepristone Approved drug PDB Ligand Immunopharmacology Ligand 2805 Mifeprex®, RU-486, RU486
miltefosine Approved drug Immunopharmacology Ligand 11355 D-18506, D18506, Impavido®, Miltex®, n-hexadecylphosphorylcholine
 
N Back to top
nivolumab Approved drug Immunopharmacology Ligand 7335 BMS-936558, MDX-1106, ONO-4538, Opdivo®
 
P Back to top
peginterferon alfa-2b Approved drug Immunopharmacology Ligand 7462 PegIntron®, Sylatron®
penicillamine Approved drug PDB Ligand Immunopharmacology Ligand 7264 Cuprimine®
PGE2 Approved drug PDB Ligand Immunopharmacology Ligand 1883 Cervidil®, minprositin E2, minprostin E2, Propess®, prostaglandin E2
prednisolone Approved drug PDB Ligand Immunopharmacology Ligand 2866 DELTA.1-Cortisol, Orapred®, Pediapred®
 
R Back to top
rituximab Approved drug Immunopharmacology Ligand 6780 HSDB 7455, IDEC-C2B8, MabThera®, Rituxan®
 
S Back to top
salbutamol Approved drug Immunopharmacology Ligand 558 albuterol, SCH-13949W, Ventolin®
salicylic acid Approved drug PDB Ligand Immunopharmacology Ligand 4306 Bazuka Extra Strength Gel®, salicylate
 
T Back to top
thalidomide Approved drug Immunopharmacology Ligand 7327 K-17
tiotropium Approved drug Immunopharmacology Ligand 367 BA-679-BR, Spiriva®