CX3CL1   Click here for help

GtoPdb Ligand ID: 856

Synonyms: fractalkine | neurotactin
Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: This is the only member of the CX3C chemokine family [1].
Species: Human
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Chemokines
Synonyms Click here for help
fractalkine | neurotactin
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
CX3CL1 C-X3-C motif chemokine ligand 1 Human chemokine (C-X3-C motif) ligand 1 ABCD-3, C3Xkine, chemokine (C-X3-C motif) ligand 1, CXC3, CXC3C, fractalkine, neurotactin, NTN, SCYD1, small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin)
Database Links Click here for help
Specialist databases
GPCRdb Ligand CX3CL1
Other databases
Ensembl Gene ENSG00000006210 (Hs)
GtoPdb PubChem SID 135651730
Human Protein Atlas ENSG00000006210 (Hs)
OMIM 601880 (Hs)
RefSeq Protein NP_002987 (Hs)
UniProtKB P78423 (Hs)
Wikipedia CX3CL1