peginterferon alfa-2b

Ligand id: 7462

Name: peginterferon alfa-2b

Compound class Peptide or derivative
Approved drug? Yes (EMA (2000), FDA (2001))
International Nonproprietary Names
INN number INN
7909 peginterferon alfa-2b
PegIntron® | Sylatron®
Peginterferon alfa-2b is a pegylated interferon protein. Conjugation with polyethylene glycol (PEG) is a strategy commonly used to protect peptide drugs from in vivo proteolytic breakdown to increase their biological half-life and duration of action. It is on the World Health Organization's List of Essential Medicines (link to 2015 list).
Database Links
Specialist databases
IMGT/mAb-DB 627
Other databases
ChEMBL Ligand CHEMBL1201561
DrugBank Ligand DB00022
GtoPdb PubChem SID 187051765
Search PubMed clinical trials peginterferon alfa-2b
Search PubMed titles peginterferon alfa-2b
Search PubMed titles/abstracts peginterferon alfa-2b
Wikipedia Peginterferon alfa-2b