ipilimumab   Click here for help

GtoPdb Ligand ID: 6888

Synonyms: MDX-010 | MDX-101 | MDX-CTLA-4 | Yervoy®
Approved drug Immunopharmacology Ligand
ipilimumab is an approved drug (FDA and EMA (2011))
Compound class: Antibody
Comment: Ipilimumab is an anti-CTLA-4 monoclonal antibody. It is likely the subject of patent WO2001014424 [4], as antibody 10D1 which was investigated further, claimed in patent EP1503794 [1]. Ipilimumab is an immune checkpoint inhibitor.
Click here for help

Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

✖

View interactive charts of activity data across species
Classification Click here for help
Compound class Antibody
Ligand families/groups Immune checkpoint modulators
Approved drug? Yes (FDA and EMA (2011))
International Nonproprietary Names Click here for help
INN number INN
8568 ipilimumab
Synonyms Click here for help
MDX-010 | MDX-101 | MDX-CTLA-4 | Yervoy®
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 180
Other databases
GtoPdb PubChem SID 178103470
PubChem SID 178103470
Search PubMed clinical trials ipilimumab
Search PubMed titles ipilimumab
Search PubMed titles/abstracts ipilimumab
Wikipedia Ipilimumab