compound 1 [PMID: 25241924]   Click here for help

GtoPdb Ligand ID: 7801

Compound class: Peptide or derivative
Comment: Lipopeptide agonist of the apelin receptor. This palmitoylated peptide is the first of its kind found to be an agonist at this receptor.
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Peptide Sequence Click here for help
VTLPLWATYTYR
Palmitate-Val-Thr-Leu-Pro-Leu-Trp-Ala-Thr-Tyr-Thr-Tyr-Arg-NH2
Post-translational Modification
The N-terminal valine residue is linked to a palmitate chemical group, and the C-terminal arginine residue has an amide group attached.