galectin-3 binding protein   Click here for help

GtoPdb Ligand ID: 6615

Synonyms: L3 antigen | Mac-2-binding protein | MAC-2-BP
Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: Galectin 3 binding protein binds galectin-3. The galectin 3 binding protein/galectin-3 interaction appears to play a critical role in venous thrombosis formation in animal models. In human patients, elevated circulating galectin-3 binding protein levels correlate with acute venous thrombosis [1].
Species: Human
Peptide Sequence Click here for help
VNDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGSGPIMLDEVQCTGTEA
SLADCKSLGWLKSNCRHERDAGVVCTNETRSTHTLDLSRELSEALGQIFDSQRGCDLSISVNVQGEDALGFCGHTVILTA
NLEAQALWKEPGSNVTMSVDAECVPMVRDLLRYFYSRRIDITLSSVKCFHKLASAYGARQLQGYCASLFAILLPQDPSFQ
MPLDLYAYAVATGDALLEKLCLQFLAWNFEALTQAEAWPSVPTDLLQLLLPRSDLAVPSELALLKAVDTWSWGERASHEE
VEGLVEKIRFPMMLPEELFELQFNLSLYWSHEALFQKKTLQALEFHTVPFQLLARYKGLNLTEDTYKPRIYTSPTWSAFV
TDSSWSARKSQLVYQSRRGPLVKYSSDYFQAPSDYRYYPYQSFQTPQHPSFLFQDKRVSWSLVYLPTIQSCWNYGFSCSS
DELPVLGLTKSGGSDRTIAYENKALMLCEGLFVADVTDFEGWKAAIPSALDTNSSKSTSSFPCPAGHFNGFRTVIRPFYL
TNSSGVD