d(CH2)5[Tyr(Me)2,Thr4,Phe(3I,4N3)-NH29]OVT   Click here for help

GtoPdb Ligand ID: 2219

Synonyms: d(CH2)5[Tyr(Me)2,Thr4,Orn8,Phe(3I,4N3)-NH29]vasotocin | I-ZOTA
Compound class: Peptide or derivative
Comment: Synthetic analogue of vasotocin
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Peptide Sequence Click here for help
CYITNCPXF
Pmp-Tyr(Me)-Ile-Thr-Asn-Cys-Pro-Orn-Phe(3I,4N3)-NH2
Chemical Modification
N-terminal cysteine of the natural sequence is replaced by Pmp (p-methoxyphenol group); tyrosine residue 2 is methylated; N-terminal phenylalanine residue is modified with iodine on carbon 3 and 3 nitrogens on carbon 4, and amidated