FSH   Click here for help

GtoPdb Ligand ID: 1157

Synonyms: follitropin | human follicle stimulating hormone
Approved drug
FSH is an approved drug (FDA (1997))
Compound class: Endogenous peptide in human, mouse or rat
Comment: FSH is a 35.5 kDa glycoprotein heterodimer, consisting of an alpha (CGA) and a beta polypeptide (FSHB) subunit. This entry also represents urofollitropin, which is a purified form of FSH that is extracted from human menopausal urine.
Species: Human
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: fsh

Subunits
glycoprotein hormone common alpha subunit
FSH β subunit
Peptide Sequence Click here for help
CYXXNCPLG
H-DL-Cys(1)-DL-Tyr-DL-xiIle-DL-xiThr-DL-Asn-DL-Cys(1)-DL-Pro-DL-Leu-Gly-NH2
HELM Notation Click here for help
PEPTIDE1{(C,[dC]).(Y,[dY]).[*C(=O)C(C(C)CC)N* |$_R2;;;;;;;;;_R1$|].[*C(=O)C(C(C)O)N* |$_R2;;;;;;;;_R1$|].(N,[dN]).(C,[dC]).(P,[dP]).(L,[dL]).G.[am]}$PEPTIDE1,PEPTIDE1,1:R3-6:R3$$$V2.0