KBP-066   Click here for help

GtoPdb Ligand ID: 10660

Synonyms: DACRA | KBP 066 | KBP066
Compound class: Peptide or derivative
Comment: KBP-066 is a Dual Amylin and Calcitonin Receptor Agonist (DACRA), which are a class of peptide, which distinguish themselves from amylin agonists as they activate both the amylin receptor and the calcitonin receptor in a prolonged fashion.
Peptide Sequence Click here for help
Ac-CSNLSTCXLGRLSQDLHRLQTYPKTDVGANAP-NH2
Ac-Cys-Ser-Asn-Leu-Ser-Thr-Cys-X-Leu-Gly-Arg-Leu-Ser-Gln-Asp-Leu-His-Arg-Leu-Gln-Thr-Tyr-Pro-Lys-Thr-Asp-Val-Gly-Ala-Asn-Ala-Pro-NH2
Chemical Modification
KBP-066 consists of an NH2-terminal acetyl group (Ac), an COOH-terminal amide group, and a 2-aminoisobutyric acid modification symbolized by an X.