danaparoid

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Ligands
danaparoid

GtoPdb Ligand ID: 6804

Synonyms: ORG-10172 | Orgaran®

danaparoid is an approved drug (FDA (1996), still marketed outside the U.S.)

Comment: Danaparoid sodium is an anticoagulant that works by inhibiting activated factor X. It is no longer marketed in the US but is still available in other countries. As this drug is a mixture of components (heparan sulfate, dermatan sulfate, and chondroitin sulfate) we are unable to give structural information.

View more information in the IUPHAR Pharmacology Education Project: danaparoid

Summary
Biological activity
Clinical data
References

References
1. Cziraky MJ, Spinler SA. (1993) Low-molecular-weight heparins for the treatment of deep-vein thrombosis. Clin Pharm, 12 (12): 892-9. [PMID:8137606]
2. Nakase J, Toribatake Y, Mouri Y, Seki H, Kitaoka K, Tomita K. (2009) Heparin versus danaproid for prevention of venous thromboembolism after hip surgery. J Orthop Surg (Hong Kong), 17 (1): 6-9. [PMID:19398784]

References

1. Cziraky MJ, Spinler SA. (1993)
Low-molecular-weight heparins for the treatment of deep-vein thrombosis.
Clin Pharm, 12 (12): 892-9. [PMID:8137606]

2. Nakase J, Toribatake Y, Mouri Y, Seki H, Kitaoka K, Tomita K. (2009)
Heparin versus danaproid for prevention of venous thromboembolism after hip surgery.
J Orthop Surg (Hong Kong), 17 (1): 6-9. [PMID:19398784]