R-715   Click here for help

GtoPdb Ligand ID: 661

Synonyms: [Ac-Lys-[d-βNal7,Ile8]des-Arg9]bradykinin | R 715 | R715
Compound class: Peptide or derivative
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
References
1. Allogho SN, Gobeil F, Pheng LH, Nguyen-Le XK, Neugebauer W, Regoli D. (1995)
Kinin B1 and B2 receptors in the mouse.
Can J Physiol Pharmacol, 73 (12): 1759-64. [PMID:8834490]
2. Gobeil F, Neugebauer W, Filteau C, Jukic D, Allogho SN, Pheng LH, Nguyen-Le XK, Blouin D, Regoli D. (1996)
Structure-activity studies of B1 receptor-related peptides. Antagonists.
Hypertension, 28 (5): 833-9. [PMID:8901831]
3. MacNeil T, Feighner S, Hreniuk DL, Hess JF, Van der Ploeg LH. (1997)
Partial agonists and full antagonists at the human and murine bradykinin B1 receptors.
Can J Physiol Pharmacol, 75: 735-740. [PMID:9276157]