B-9858   Click here for help

GtoPdb Ligand ID: 654

Synonyms: B 9858 | Lys-Lys-[Hyp3, Igl5, D-Igl7, Oic8]des-Arg9-BK
Compound class: Peptide or derivative
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
References
1. Jones C, Phillips E, Davis C, Arbuckle J, Yaqoob M, Burgess GM, Docherty RJ, Webb M, Bevan SJ, McIntyre P. (1999)
Molecular characterisation of cloned bradykinin B1 receptors from rat and human.
Eur J Pharmacol, 374: 423-433. [PMID:10422787]
2. Leeb T, Mathis SA, Leeb-Lundberg LM. (1997)
The sixth transmembrane domains of the human B1 and B2 bradykinin receptors are structurally compatible and involved in discriminating between subtype-selective agonists.
J Biol Chem, 272: 311-317. [PMID:8995263]
3. MacNeil T, Feighner S, Hreniuk DL, Hess JF, Van der Ploeg LH. (1997)
Partial agonists and full antagonists at the human and murine bradykinin B1 receptors.
Can J Physiol Pharmacol, 75: 735-740. [PMID:9276157]
4. Regoli D, Nsa Allogho S, Rizzi A, Gobeil FJ. (1998)
Bradykinin receptors and their antagonists.
Eur J Pharmacol, 348 (1): 1-10. [PMID:9650825]