μ-conotoxin GIIIA   Click here for help

GtoPdb Ligand ID: 2630

Synonyms: Geographutoxin I | GTx-I | Myotoxin I
Compound class: Peptide or derivative
Comment: From Conus geographus (Geography cone)
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
References
1. Chahine M, Bennett PB, George Jr AL, Horn R. (1994)
Functional expression and properties of the human skeletal muscle sodium channel.
Pflugers Arch, 427 (1-2): 136-42. [PMID:8058462]
2. Chen LQ, Chahine M, Kallen RG, Barchi RL, Horn R. (1992)
Chimeric study of sodium channels from rat skeletal and cardiac muscle.
FEBS Lett, 309 (3): 253-7. [PMID:1325372]
3. Safo P, Rosenbaum T, Shcherbatko A, Choi DY, Han E, Toledo-Aral JJ, Olivera BM, Brehm P, Mandel G. (2000)
Distinction among neuronal subtypes of voltage-activated sodium channels by mu-conotoxin PIIIA.
J Neurosci, 20 (1): 76-80. [PMID:10627583]