[Leu31,Pro34]PYY (human)   Click here for help

GtoPdb Ligand ID: 1527

Synonyms: human [Leu31,Pro34] peptide tyrosine tyrosine | human [Leu31,Pro34] peptide YY
Compound class: Peptide or derivative
Comment: Synthetic analogue of human PYY
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
References
1. Gehlert DR, Beavers LS, Johnson D, Gackenheimer SL, Schober DA, Gadski RA. (1996)
Expression cloning of a human brain neuropeptide Y Y2 receptor.
Mol Pharmacol, 49 (2): 224-8. [PMID:8632753]
2. Gehlert DR, Schober DA, Gackenheimer SL, Beavers L, Gadski R, Lundell I, Larhammar D. (1997)
[125I]Leu31, Pro34-PYY is a high affinity radioligand for rat PP1/Y4 and Y1 receptors: evidence for heterogeneity in pancreatic polypeptide receptors.
Peptides, 18 (3): 397-401. [PMID:9145427]
3. Hu Y, Bloomquist BT, Cornfield LJ, DeCarr LB, Flores-Riveros JR, Friedman L, Jiang P, Lewis-Higgins L, Sadlowski Y, Schaefer J et al.. (1996)
Identification of a novel hypothalamic neuropeptide Y receptor associated with feeding behavior.
J Biol Chem, 271 (42): 26315-9. [PMID:8824284]