KBP-066

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Ligands
KBP-066

GtoPdb Ligand ID: 10660

Synonyms: DACRA | KBP 066 | KBP066

Compound class: Peptide or derivative

Comment: KBP-066 is a Dual Amylin and Calcitonin Receptor Agonist (DACRA), which are a class of peptide, which distinguish themselves from amylin agonists as they activate both the amylin receptor and the calcitonin receptor in a prolonged fashion.

Summary
Biological activity
References
Structure

References
1. Sonne N, Larsen AT, Andreassen KV, Karsdal MA, Henriksen K. (2020) The Dual Amylin and Calcitonin Receptor Agonist, KBP-066, Induces an Equally Potent Weight Loss Across a Broad Dose Range While Higher Doses May Further Improve Insulin Action. J Pharmacol Exp Ther, 373 (1): 92-102. [PMID:31992608]

References

1. Sonne N, Larsen AT, Andreassen KV, Karsdal MA, Henriksen K. (2020)
The Dual Amylin and Calcitonin Receptor Agonist, KBP-066, Induces an Equally Potent Weight Loss Across a Broad Dose Range While Higher Doses May Further Improve Insulin Action.
J Pharmacol Exp Ther, 373 (1): 92-102. [PMID:31992608]