avelumab

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Ligands
avelumab

GtoPdb Ligand ID: 8735

Synonyms: Bavencio® | MSB-0010718C | MSB0010718C

avelumab is an approved drug (EMA & FDA (2017))

Comment: Avelumab is a programmed death-ligand 1 (PD-L1; CD274) blocking human IgG1 lambda monoclonal antibody . It is the first drug approved for the treatment of Merkel cell carcinoma (MCC).
Peptide sequence and structural information for this antibody are available from its IMGT/mAb-db record.

Summary
Biological activity
Clinical data
References
Immunopharmacology

Immunopharmacology Comments
Avelumab is included in GtoImmuPdb as it is an immune checkpoint inhibitor, a mechanism of action now widely accepted as efficacious for cancer immunotherapy [2-3].

Immunopharmacology Comments

Avelumab is included in GtoImmuPdb as it is an immune checkpoint inhibitor, a mechanism of action now widely accepted as efficacious for cancer immunotherapy [2-3].