Synonyms: TPCA-1 | TPCA1
Compound class:
Synthetic organic
Comment: This compound is an inhibitor of IKKβ (IKK2) [4].
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
|
Immunopharmacology Comments |
IKK2 is a protein subunit of the IκB kinase (IKK). Inhibition of IKK and IKK-related kinases has been investigated as an intervention point for the treatment of inflammatory diseases (and cancer) [3]. |