blisibimod   Click here for help

GtoPdb Ligand ID: 9518

Synonyms: A-623 | AGP3 peptibody [5] | AMG 623 | Fc-Agp-3 [1]
Immunopharmacology Ligand
Compound class: Peptide or derivative
Comment: Blisibimod is a peptibody fusion containing four BAFF binding domains fused to a human Fc domain. By sequestering circulating BAFF ligand, it acts as a functional antagonist of BAFF interaction with the TACI receptor on B cells.
Peptide sequences and structural information for this peptide are available from its IMGT/mAb-DB entry. The peptide sequence for blisibimod is claimed in Amgen's patent WO2002092620 [5].
No information available.
Summary of Clinical Use Click here for help
Click here to link to the full list of blisibimod trials registered with ClinicalTrials.gov.